From Pittsburgh / Washington, PA:
I-79 South to Exit 14 (Rt. 21 Waynesburg)
Turn right onto Rt 21 West and go 2 miles
From Uniontown:
Route 21 West becomes High Street
From Morgantown, WV:
I-79 North to Exit.14 (Rt. 21 Waynesburg). Turn right onto Rt. 21 and go 2 miles